Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8+T cell function and its impact against pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is currently difficult to treat, even when therapies are Dishwasher ComfortLift End Stopper combined with immune checkpoint blockade (ICB).A novel strategy for immunotherapy would be to maximize the therapeutic potential of oncolytic viruses (OVs), which have been proven to engage the regulation of tumor micr